CHOLINE


  • Dosing
    		•
  • Therapeutic Uses
    		•
  • Sources
    		•
  • High-Risk Groups
    		•
  • Deficiency Consequences
    		•
  • Toxicity/Side Effects
    		•
  • Contraindications
    		•
  • Additional Information
    		•
  • Drug Interactions
    		•




    United States Recommended Dietary Allowances
    No recommended dietary allowances or safe and adequate requirements exist.








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    Therapeutic Uses
    Used in the production of phospholipids (a component of cell membranes). It is a precursor to acetylcholine, which improves memory function. Choline is a methyl donor for many metabolic processes. It can enhance phospholipid biosynthesis in the brain and nerve tissue thus influencing brain function. It prevents fat deposition into the liver and can transport fat from the liver.





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    Sources
    Liver, eggs, yolk, beef steak, peanuts, cauliflower, wheat germ and brewer's yeast.







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    High-Risk/Increased Need Groups
    None identified.







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    Deficiency Consequences
    No clear deficiency syndrome has been identified in humans, however in animals fatty infiltrate of liver and liver dysfunction, abnormal kidney function, infertility, growth impairment, bone abnormalities, reduced red blood cell formation, memory loss and liver cancer have been identified.





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    Toxicity/Side Effects
    Nothing has been identified, however taking the oral form can produce an unpleasant fishy odor from bacterial breakdown to trimethylamine in the gastrointestinal tract.







    Table of Contents Choline Member Doctors TCCA Home Page




    Contraindications
    None noted.







    Table of Contents Choline Member Doctors TCCA Home Page





    Additional Information/Precautions
    Choline is a lipotropic (fat emulsifying) agent. It has a possible role in brain development, neurological function, liver function and prevention of cancer. All tissues take up choline. Choline is a component of both lecithin and sphingomyelin in the brain and nerve tissue.






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    Drug Interactions
    None noted.








    Table of Contents Choline Member Doctors TCCA Home Page




    References
    1. Chiropractic Nutritional Reference 1987 Edition, James M. Gerber, DC
    2. Facts and Comparisons Drug Information, Updated Monthly, Loose-leaf drug information service
    3. RA Pharmacist Guide to Vitamins, Minerals and Herbs and Other Nutrients, 1998